Introduction

Cellulitis is a common bacterial skin infection.

Affected skin may appear swollen, painful, and warm to the touch (Santos et al., 2018).

It mainly affects the lower legs, face and arms.

Hesitation to treat the disease can affect lymph nodes and the bloodstream, becoming life-threatening.

 

 

 

Causes

Bacterial infection.

The bacteria enter through openings and skin cracks.

Affects the deep layers of the skin.

Streptococcus and staphylococcus infections are most common (Webb et al., 2020).

 

 

 

 

Signs & Symptoms

 

 

 

Erythema

Edema

Pain in the affected area.

Warmth

Fever

Blisters

Skin dimpling (Sullivan & Barra 2018).

 

 

 

4

Pathophysiology

Bacteria invades open skin.

It overwhelms neutrophils, eosinophils, and basophils, causing inflammation over 1st 72 hrs. (Sullivan & Barra 2018).

As infection progress it invades healthier cells.

Blisters formulate in the affected area.

 

 

 

 

 

Differential Diagnosis

Lymphatic filariasis- the disease is caused by microscopic parasites, and thread-like worms.

 

Chronic venous insufficiency- occurs when your lower legs veins fail to deliver back blood to the heart (Webb et al., 2020).

 

Acute deep venous thrombosis – blood clots in one or more deep veins.

 

Lipedema – excessive fat remains and accumulates in the victim.

 

 

 

Diagnosis

– Skin examination

CBC

Gram stain and culture of fluid from abscess and bulla (Sullivan & Barra 2018).

Culture of the primary lesion by aspiration.

Blood cultures often negative (only 10% positive)

Wound cultures often negative (70%)

Purulence = often S. Aureus.

Animal bites = often gram-negative bacteria.

 

 

 

Risk Factors

Weakened immune system

Lymphedema

History of cellulitis

Obesity

Skin conditions

Injury

 

 

 

 

Treatment

Outpatient: Oral antibiotics.

Amoxicillin is commonly used due to its bioavailability

250-500 mg PO 3 x daily (Webb et al., 2020).

Usually 5 to 10 days, depending on severity.

Follow up in 3 days regarding progress

No improvement or new fever = ER visit.

 

 

 

Teaching

Keep the infected area clean.

Record temperature daily for a week.

Maintain hygiene to avoid infection spread (Webb et al., 2020).

Take entire abx supply until gone to avoid reinfection.

OTC drugs to use for pain

Acetaminophen

325-1000 mg PO q 8 hrs

Ibuprofen

200-600 mg PO q 8 hrs

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